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RHODIOLA (R. rosea), or roseroot, may be a beneficial treatment option for major depressive disorder (MDD), according to results of a study. All of the study’s 57 adult participants, with MDD enrolled, received 12 weeks of standardized R. rosea extract, the anti-depressamt sertraline, or placebo.

Patients taking Rhodiola had 1.4 times the odds of improvement, and patients on sertraline had 1.9 times the odds of improvement versus those on a placebo.

However, patients on sertraline experienced twice the side effects – most commonly nausea and sexual dysfunction — than those on Rhodiola.

Other herbs which can help alleviate depression include St. John’s Wort, Rosemary, Magnolia, Withania and Korean Ginseng.